Frontiers of the New Institutional Economics

Book Description

The New Institutional Economics incorporates a theory of institutions into economics. It builds upon the fundamental assumptions of scarcity and competition but abandons institutional rationality. Consequently, NIE assumes that individuals make choices based on incomplete information and limited mental capacity, forming institutions to reduce uncertainty in human exchange. These insights have implications for technological change, property rights, and public choice. The Frontiers of the New Institutional Economics presents new essays written specifically for this volume. These essays Provide an introduction to the nature and practice of the New Institutional Economics, with a special emphasis on economic history and political economy. Among the contributors are Nobel Prize winners Douglass North and Robert Fogel.

Key Features
* Contains essays by Nobel Prize winners Douglass North and Robert Fogel
* Presents a field of economics useful to students of political science and sociology.
* Applicable to studies of technological change, property rights, and public choice

Institutional Pathways to Equity: Addressing Inequality Traps (New Frontiers of Social Policy Series)

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Institutional Pathways to Equity: Addressing Inequality Traps (New Frontiers of Social Policy Series)
Michael Walton , Anthony J. Bebbington , and Anis A. Dani
Manufacturer: World Bank Publications
ProductGroup: Book
Binding: Paperback

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The New Institutional Economics of Corruption (Routledge Frontiers of Political Economy)

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The New Institutional Economics of Corruption (Routledge Frontiers of Political Economy)
Joha Lambsdorff
Manufacturer: Routledge
ProductGroup: Book
Binding: Hardcover

General | Popular Economics | Business & Investing | Subjects | Books

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The Institutional Economics of Corruption and Reform: Theory, Evidence and Policy

ASIN: 0415333687

Book Description

Corruption is an important phenomenon in the world today affecting a wide range of economies across the world. Measuring and explaining the effect of corruption is no easy task, yet this book sets about it with real vigor.

Examining the institutional aspects of corrupt transactions, this book provides a new perspective toward anti-corruption policies. It does so by focusing on the role of institutions such as individual attitudes; social norms; and mafia type organizations.

With an international troop of contributors, this book will impress academics with an interest in institutional economics, sociology and corruption. It will also prove to be a useful addition to policy-makers in the sphere of fighting corruption.

Economic Institutions in a Dynamic Society: Search for a New Frontier : Proceedings of a Conference Held by the International Economic Association I

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Economic Institutions in a Dynamic Society: Search for a New Frontier : Proceedings of a Conference Held by the International Economic Association I
Takashi Shiraishi
Manufacturer: Palgrave Macmillan
ProductGroup: Book
Binding: Hardcover

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The Frontiers of the New Institutional Economics

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The Frontiers of the New Institutional Economics
John N. Drobak
Manufacturer: Academic Press
ProductGroup: Book
Binding: Paperback
ASIN: B000OH4GS6

In Action: Implementing Training Scorecards (In Action Case Study Series)
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A Winning Score for the Reader

In Action: Implementing Training Scorecards (In Action Case Study Series)
Lynn Schmidt
Manufacturer: ASTD
ProductGroup: Book
Binding: Paperback

General | Business & Investing | Subjects | Books
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How to Measure Training Results : A Practical Guide to Tracking the Six Key Indicators

The Leadership Scorecard: ROI for Leaders (Improving Human Performance Series)

Evaluating E-Learning (The Astd E-Learning Series)

Running Training Like a Business: Delivering Unmistakable Value

The Workforce Scorecard: Managing Human Capital To Execute Strategy

ASIN: 1562863142

Book Description

How do you know that your HR or training department has accomplished its objectives? Using a training scorecard provides a structure for establishing, tracking, compiling, and communicating results. This volume presents case studies that best illustrate how to use and implement training scorecards.

Customer Reviews:

A Winning Score for the Reader.......2003-08-12

This book is a Win for those in the HR and training profession on how to use the scoreboard methods in training. The chapter on the Value of Training Scorecards by Ms Schmidt is a must read. The case studies by those in the field are great examples of how to apply the concepts. This book should be in everyones reference book shelf. Jack Phillips and Lynn Schmidt are a great team in presenting concepts of ROI and value of training scorecards. Thanks to the editors and the contributors for providing this valuable resource. I have many years of experience in training and management development from postions in telecom and computers.

Implementing Training Scorecards: In Action.

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Implementing Training Scorecards: In Action.
Jack J. Phillips
Manufacturer: Publisher Unknown
ProductGroup: Book
Binding: Paperback
ASIN: B000UYIS5K

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Implementing Training Scorecards: In Action.
Jack J. Phillips
Manufacturer: Phillips, Jack J. and Lynn Schmidt (eds). Implementing Training Scorecards: In Action. Alexandria, VA: ASTD Press, 2003. Quality paperback. 202pp. Near new, clean, tight and bright condition, with lightly bumped corner.
ProductGroup: Book
Binding: Paperback
ASIN: B000TAA97U

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Implementing Training Scorecards: In Action.

ProductGroup: Book
Binding: Paperback
ASIN: B000IC5R80

Book Description

Stargazers who may have missed the last total solar eclipse of the 20th century this past summer have just been given another chance to observe this "once in a lifetime" occurrence. Inside Glorious Eclipses they will find startling images and rich personal accounts that fully capture this event and other recent eclipses. The book will also insure that readers will not miss another eclipse in the next 60 years! Specially designed in a beautiful, large format, the volume portrays eclipses of all kinds--lunar, solar, and those occurring elsewhere in the Solar System and beyond. Brunier and Luminet have gathered together all aspects of eclipses, and carefully selected a host of lavish images. The authors detail the history of eclipses, the celestial mechanics involved, their observation, and scientific interest. Personal accounts of recent eclipses are also included as well as all relevant information about forthcoming eclipses up to 2060. Complete with NASA maps and data, Glorious Eclipses is the ultimate source for all those interested in these remarkable (and rare) celestial events. Serge Brunier is chief editor of the journal Ciel et Espace, a photo-journalist, and the author of many nonfiction books aimed at both specialists and the general public. Jean-Pierre Luminet is an astrophysicist at the Paris-Meudon Observatory and director of research at the Centre pour la Recherche Scientifique. He is the author of many popular astronomy books, including Black Holes (Cambridge University Press, 1992).

Customer Reviews:

Beautiful eclipse photography.......2001-02-15

I have an extensive collection of eclipse books, and this one really stands out in the crowd. For one thing, it's easily the largest-format eclipse book I've seen; I'd call it a coffee-table book. But what is really striking are the beautiful photographs. The reproduction is outstanding, and the large size makes the photos particularly vivid.

I haven't read the text yet, and so I can't comment on it, but the overall impression is that this book is a must-have for anybody interested in the beauty of total solar eclipses.

Book Description

Chemical data analysis, with aspects of metrology in chemistry and chemometrics, is an evolving discipline where new and better ways of doing things are constantly being developed. This book makes data analysis simple by demystifying the language and whenever possible giving unambiguous ways of doing things. Based on author D. Brynn Hibberts lectures on data analysis to undergraduates and graduate students, Data Analysis for Chemistry covers topics including measurements, means and confidence intervals, hypothesis testing, analysis of variance, and calibration models. The end result is a compromise between recipes of how to perform different aspects of data analysis, and basic information on the background principles behind the recipes to be performed. An entry level book targeted at learning and teaching undergraduate data analysis, Data Analysis for Chemistry makes it easy for readers to find the information they are seeking to perform the data analysis they think they need.

Data Analysis for Chemistry: An Introductory Guide for Students and Laboratory Scientists

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Data Analysis for Chemistry: An Introductory Guide for Students and Laboratory Scientists
D. B. Gooding, J. Justin Hibbert
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback
ASIN: B000OKKYNO

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Data Analysis for Chemistry: An Introductory Guide for Students and Laboratory Scientists
D. Brynn; Gooding, J. Justin Hibbert
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback
ASIN: B000OKJ7MS

Book Description

DNA from A to Z is the latest edition of one of AACC's most popular books! Updated and with many new entries, the new edition reflects the many changes that have occurred in the field of DNA in the last five years, including the completion of the sequencing of the Human Genome. Illustrated with multiple photographs and images, this guide is a classic, easy-to-read reference that can serve as a foundation for further inquiry for professionals and the lay public alike, or stand alone. Here's what "Nature" said about the first edition, DNA Simplified: The Hitchhiker's Guide to DNA -- "Farkas has compiled a dictionary of the essential ingredients for understanding molecular genetics and biology. But this is not another monotonous glossary of specialist lingo. The jargon of DNA technology has been translated into simple dialogue and familiar analogies, stripped down to the bare essentials. The book is an entertaining read, with the science taking on a personality of its own. Of particular appeal to biomedical scientists, the book paces through state-of-the-art DNA technology applied to clinical diagnostics. It provides an impressive account of recent innovations, as well as fresh adaptations of traditional methods. The book is relevant to anyone from the specialist to the uninitiated."

Biomarkers responses of the earthworm Eisenia fetida to acetochlor exposure in OECD soil [An article from: Chemosphere]

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Biomarkers responses of the earthworm Eisenia fetida to acetochlor exposure in OECD soil [An article from: Chemosphere]
N.W. Xiao , Y. Song , F. Ge , X.H. Liu , and Z.Y. Ou-Yang
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000PAU3P2

Book Description

This digital document is a journal article from Chemosphere, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
To examine the potential of a suite of biomarkers as early warning indicators of environmental pollution, sperm count, neutral red retention time (NRRT) and DNA damage were measured in earthworm Eisenia fetida exposed to increasing concentrations of acetochlor in OECD soil. The neutral red retention time of earthworms coelomocytes was sensitive to acetochlor pollution, and decreased significantly when the concentration was more than 10mgkg^-^1 after 30 and 60 days of exposure (P <0.05). The reduced neutral red retention time correlated with the soil acetochlor residual. Sperm count decreased significantly at the concentrations of 40 and 80mgkg^-^1 after 15 days of exposure (P <0.05). The DNA damage of earthworms coelomocytes increased significantly after 30 days of exposure at the highest concentration (80mgkg^-^1; P <0.05). Earthworms were under physiological stress at field dose of acetochlor (10mgkg^-^1). Higher concentrations of acetochlor caused sperm count decrease and DNA damage of earthworms. Such a suite of biomarkers could serve as indicators of the health of the soil environment and to evaluate the toxicity of acetochlor on earthworms or as a means of monitoring soil acetochlor pollution.

Cadmium induces DNA damage in tobacco roots, but no DNA damage, somatic mutations or homologous recombination in tobacco leaves [An article from: Mut.Res.-Genetic ... Toxicology and Environmental Mutagenesis]

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Cadmium induces DNA damage in tobacco roots, but no DNA damage, somatic mutations or homologous recombination in tobacco leaves [An article from: Mut.Res.-Genetic ... Toxicology and Environmental Mutagenesis]
T. Gichner , Z. Patkova , J. Szakova , and K. Demnerova
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Comets, Meteors & Asteroids | Astronomy | Science | Subjects | Books

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000RQZ246

Book Description

This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The heavy metal cadmium (Cd^2^+) applied on tobacco roots in the form of cadmium chloride, induced significantly higher levels of DNA damage as measured by the cellular Comet assay than did treatment of isolated root nuclei, analyzed by use of the acellular Comet assay. DNA damage induced by Cd^2^+ in roots of a transgenic catalase-deficient tobacco line (CAT1AS) was higher than in wild-type tobacco (SR1) roots. In contrast to treatment with the positive control ethyl methanesulphonate, Cd^2^+ induced no significant DNA damage in leaf nuclei, and neither somatic mutations, nor homologous recombination as measured by the GUS genereactivation assay, were observed in leaves. Analysis of the accumulation of cadmium by inductively coupled plasma optical emission spectrometry demonstrates that roots accumulate almost 50-fold more cadmium than above-ground parts of the tobacco seedlings. This may explain the absence of Cd^2^+ genotoxicity in leaves.

Directly light scattering imaging of the aggregations of biopolymer bound chromium(III) hydrolytic oligomers in aqueous phase and liquid/liquid interface [An article from: Analytica Chimica Acta]

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Directly light scattering imaging of the aggregations of biopolymer bound chromium(III) hydrolytic oligomers in aqueous phase and liquid/liquid interface [An article from: Analytica Chimica Acta]
J. Ling , C.Z. Huang , and Y.F. Li
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000RR8JB8

Book Description

This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Investigations of inorganic oligomers are important in both chemistry and physiology. In this contribution, we propose a laser induced light scattering imaging (LSI) and a total internal reflected light scattering imaging (TIR-LSI) technique, and apply them to characterize the interactions of inorganic oligomers with biopolymer in aqueous phase and at liquid/liquid interface, respectively. In aqueous medium, synthetic chromium(III) hydrolytic oligomers (CrHO) react with DNA, and the resultant binary could be extracted into the H"2O/CCl"4 interface in the presence of triocyctyl phosphine oxide (TOPO), forming a DNA-CrHO-TOPO ternary amphipathic complex at the interface with the associate constant of 1.32x10^3mol^-^1dm^4 for a given 1.0x10^-^4moll^-^1 TOPO. Under the excitation of a 441-nm He-Cd laser light beam, the resultant light scattering and total internal reflected light scattering (TIR-LS) signals of the formed binary in aqueous phase and ternary at liquid/liquid interface could be easily captured using a common microscope coupled with a CCD camera. By digitally analyzing the CCD captures, we demonstrate that aggregations of the CrHO-DNA binary in aqueous phase and DNA-CrHO-TOPO ternary at liquid/liquid interface have occurred, respectively.

DNA damage evaluated by @cH2AX foci formation by a selective group of chemical/physical stressors [An article from: Mut.Res.-Genetic Toxicology and Environmental Mutagenesis]

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DNA damage evaluated by @cH2AX foci formation by a selective group of chemical/physical stressors [An article from: Mut.Res.-Genetic Toxicology and Environmental Mutagenesis]
C. Zhou , Z. Li , H. Diao , Y. Yu , W. Zhu , Y. Dai , and Ch
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000RR95VG

Book Description

This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
It has been reported that the phosphorylated form of histone variant H2AX (@cH2AX) plays an important role in the recruitment of DNA repair and checkpoint proteins to sites of DNA damage, particularly at double strand breaks (DSBs). Using @cH2AX foci formation as an indicator for DNA damage, several chemicals/stress factors were chosen to assess their ability to induce @cH2AX foci in a 24h time frame in a human amnion FL cell line. Two direct-acting genotoxins, methyl methanesulfonate (MMS) and N-ethyl-N-nitrosourea (ENU), can induce @cH2AX foci formation in a time- and dose-dependent manner. Similarly, an indirect-acting genotoxin, benzo[a]pyrene (BP), also induced the formation of @cH2AX foci in a time- and dose-dependent manner. Another indirect genotoxin, 2-acetyl-aminofluorene (AAF), did not induce @cH2AX foci formation in FL cells; however, AAF can induce @cH2AX foci formation in Chinese hamster CHL cells. Neutral comet assays also revealed the induction of DNA strand breaks by these agents. In contrast, epigenetic carcinogens azathioprine and cyclosporine A, as well as non-carcinogen dimethyl sulfoxide, did not induce @cH2AX foci formation in FL cells. In addition, heat shock and hypertonic saline did not induce @cH2AX foci. Cell survival analyses indicated that the induction of @cH2AX is not correlated with the cytotoxic effects of these agents/factors. Taken together, these results suggest that @cH2AX foci formation could be used for evaluating DNA damage; however, the different cell types used may play an important role in determining @cH2AX foci formation induced by a specific agent.

DNA microarray technology in toxicogenomics of aquatic models: Methods and applications [An article from: Comparative Biochemistry and Physiology, Part C]

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DNA microarray technology in toxicogenomics of aquatic models: Methods and applications [An article from: Comparative Biochemistry and Physiology, Part C]
Z. Ju , M.C. Wells , and R.B. Walter
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Bioinformatics | Biological Sciences | Science | Subjects | Books

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ASIN: B000PDT85A

Book Description

This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Toxicogenomics represents the merging of toxicology with genomics and bioinformatics to investigate biological functions of genome in response to environmental contaminants. Aquatic species have traditionally been used as models in toxicology to characterize the actions of environmental stresses. Recent completion of the DNA sequencing for several fish species has spurred the development of DNA microarrays allowing investigators access to toxicogenomic approaches. However, since microarray technology is thus far limited to only a few aquatic species and derivation of biological meaning from microarray data is highly dependent on statistical arguments, the full potential of microarray in aquatic species research has yet to be realized. Herein we review some of the issues related to construction, probe design, statistical and bioinformatical data analyses, and current applications of DNA microarrays. As a model a recently developed medaka (Oryzias latipes) oligonucleotide microarray was described to highlight some of the issues related to array technology and its application in aquatic species exposed to hypoxia. Although there are known non-biological variations present in microarray data, it remains unquestionable that array technology will have a great impact on aquatic toxicology. Microarray applications in aquatic toxicogenomics will range from the discovery of diagnostic biomarkers, to establishment of stress-specific signatures and molecular pathways hallmarking the adaptation to new environmental conditions.

DNA strand breaking capacity of acrylamide and glycidamide in mammalian cells [An article from: Mut.Res.-Genetic Toxicology and Environmental Mutagenesis]

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DNA strand breaking capacity of acrylamide and glycidamide in mammalian cells [An article from: Mut.Res.-Genetic Toxicology and Environmental Mutagenesis]
N. Puppel , Z. Tjaden , F. Fueller , and D. Marko
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

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ASIN: B000RR4LY2

Book Description

This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
We compared the DNA damaging potency of acrylamide (AA) and its metabolite glycidamide (GA) in the comet assay in cell systems differing with respect to species origin and cytochrome P450-depended monooxygenase (CYP2E1) expression (V79, Caco-2, primary rat hepatocytes). Only after 24h incubation in the highest concentration of AA (6mM) a slight but significant increase in DNA damage was observed in V79 and Caco-2 cells. In primary rat hepatocytes, however, expressing substantial amounts of CYP2E1, no induction of DNA strand breaks was found. At the end of the incubation time period (24h), still 67+/-19% of the CYP2E1 protein was detected by Western blotting. Direct treatment with GA resulted in a significant increase in DNA damage in V79 cells and primary rat hepatocytes at concentrations >=100@mM (24h). Caco-2 cells were found to be less sensitive, exhibiting an increase in DNA strand breaks at concentrations >=300@mM GA. These data confirm the higher genotoxic potential of GA compared to AA but also indicate that high expression of CYP2E1 per se is not necessarily associated with increased genotoxicity of AA. We, therefore, investigated whether the intracellular glutathione (GSH) level might be a critical determinant for the genotoxicity of AA in cells with different CYP2E1 status. Depletion of intracellular GSH by dl-buthionine-[S,R]-sulfoxime (BSO) in rat hepatocytes and V79 cells resulted in a significant induction of DNA strand breaks after incubation with 1mM AA. However, at higher concentrations (>=1.25mM) a strong increase in cytotoxicity, resulting in a severe loss of viability, was observed. In summary, the DNA strand breaking effect of AA appeared not to be directly correlated with the CYP2E1 status of the cells. Depletion of GSH is associated with an increase in AA genotoxicity but seems also to lead to a substantial enhancement of cytotoxicity.

Dual negative regulatory mechanisms of RecX on RecA functions in radiation resistance, DNA recombination and consequent genome instability in Deinococcus radiodurans [An article from: DNA Repair]

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Dual negative regulatory mechanisms of RecX on RecA functions in radiation resistance, DNA recombination and consequent genome instability in Deinococcus radiodurans [An article from: DNA Repair]
D. Sheng , R. Liu , Z. Xu , P. Singh , B. Shen , and Y Hua
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

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ASIN: B000RR38MI

Book Description

This digital document is a journal article from DNA Repair, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
RecA protein plays a central role in homologous recombination and DNA repair. RecX, a gene directly downstream in Escherichia coli and some other bacterial species, down regulates it. However, the precise mechanism of regulation of RecA by RecX is not known. In order to study the function of RecX in the highly radioresistant bacterium Deinococcus radiodurans, null and overexpression strains were constructed. Our data demonstrates that RecX represses radiation resistance, DNA recombination and consequent genome instability in the stationary phase bacteria. Further biochemical analyses reveal that RecX not only down regulates recA transcription, but also directly inhibits RecA activities in vitro. These data suggests a dual negative regulatory control of RecX on RecA functions in D. radiodurans.

Dye sensitized luminescent europium nanoparticles and its time-resolved fluorometric assay for DNA [An article from: Analytica Chimica Acta]

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Dye sensitized luminescent europium nanoparticles and its time-resolved fluorometric assay for DNA [An article from: Analytica Chimica Acta]
Y. Chen , and Z. Lu
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000PDU2GY

Book Description

This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The preparation and detection of highly luminescent aqueous europium nanoparticle labels for the time-resolved fluorometric assays has been demonstrated. The luminescent complexes included in the nanoparticle were composed of a dye sensitizer and a polyaminocarboxylate-based chelator with excellent water-solubility and a high binding constant for lanthanides. The luminescence of europium is greatly enhanced by the sensitization of the dye. The structure design of two functional entities in the single molecule made the lanthanide complex to have both strong luminescence and good aqueous solubility. SiO"2 nanoparticles containing europium complexes were prepared by the reverse microemulsion method. One particle of ~55nm in diameter has a luminescent intensity corresponding ~1300 free europium complexes and 0.61ms fluorescence lifetime. The DNA time-resolved fluorometric assay with this nanoparticle label was carried out by magnetic microbeads as solid phase carrier. The detection sensitivity with the nanoparticles is improved more than 50-fold compared with the conventional dye FITC molecules. This luminescent nanoparticle label based on dye sensitization can be applied in ultrasensitive time-resolved fluorometric assays and imaging.

The effect of oxidative metabolism on spontaneous Pol@z-dependent translesion synthesis in Saccharomyces cerevisiae [An article from: DNA Repair]

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The effect of oxidative metabolism on spontaneous Pol@z-dependent translesion synthesis in Saccharomyces cerevisiae [An article from: DNA Repair]
B.K. Minesinger , A.L. Abdulovic , T.M. Ou , and Jinks-Ro
Manufacturer: Elsevier
ProductGroup: Book
Binding: Digital

Elsevier | By Publisher | e-Docs | Formats | Books
ASIN: B000RR6KYG

Book Description

This digital document is a journal article from DNA Repair, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
DNA lesions can stall or block high-fidelity polymerases, thus inhibiting replication. To bypass such lesions, low-fidelity translesion synthesis (TLS) polymerases can be used to insert a nucleotide across from the lesion or extend from a lesion:base mispair. When DNA repair is compromised in Saccharomyces cerevisiae, spontaneous DNA lesions can lead to a novel mutational event in which a frameshift is accompanied by one or more base pair substitutions. These ''complex frameshifts'' are dependent upon the TLS polymerase Pol@z, and provide a mutational signature for mutagenic Pol@z-dependent activity. In the current study, we have found that a specific subset of the Pol@z-dependent mutational events requires oxidative metabolism. These results suggest that translesion bypass of spontaneously oxidized DNA bases can be a significant source of mutagenesis in repair compromised cells.

Book Description

The papers of this international conference present the most recent advances in atomic physics, which presently encompasses a number of branches in rapid development, representing the cutting edge of frontier physics. Some of the main topics presented are: recent advances in the study of ultra-cold matter, determination of fundamental constants, study of single atoms and molecules, atomic clocks, quantum entanglement and computing, ultrafast dynamics, quantum electro-dynamics calculations, and detection of gravitational waves. This conference is the most important international forum for atomic physics and applications.

Laser Spectroscopy: Proceedings Of The XVII International Conference

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Laser Spectroscopy: Proceedings Of The XVII International Conference
E. A. Hinds , Allister Ferguson , and Erling Riis
Manufacturer: World Scientific Publishing Company
ProductGroup: Book
Binding: Hardcover

General | Science | Subjects | Books

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All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 9812566597

Book Description

Based on a true story, "Greetings from Biloxi" is a tale of misadventures between North vs South and East vs West.

Cultures collide in this often funny, sometimes dangerous story of a professor who helps start a specialty clinic in Saudi Arabia. While Coast residents make hurricane preparations, beer-drinking Yankee inlaws rewire the patio for polka music. Tipsy Brits demonstrate the fun way to buy Persian rugs and teach the fine art of smoking the hubbly-bubbly.

In the end, they find the humor in situations and learn that, just maybe, we're not so different after all.

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